Funded by the Alzheimer’s and Dementia Research Center at Utah State University.
Nearly 50% of adults over 75 years in the United States have disabling age related hearing loss (ARHL). Yet, despite significant advances in hearing aid technology, a large percentage (78 %) of older adults with hearing loss do not own and use hearing aids. Age related hearing loss is associated with a higher incidence of dementia, social isolation, decreased cognitive functioning, poorer physical functioning and reduced quality of life. According to a 2020 Lancet Commissions report (Livingston et al., 2020), effective treatment of hearing loss improves quality of life and is associated with a reduction in new dementia cases. While studies have suggested that hearing aids improve social engagement and, in turn, cognition, there is no neurophysiological evidence supporting these observations.
We are conducting a small scale randomized controlled trial to assess the cognitive and neurophysiological benefits of hearing aids. We will measure brain activation using functional near-infrared spectroscopy (fNIRS), which is a relatively low cost, non-invasive, and portable device for assessing cortical brain changes over time. fNIRS is quiet, minimally restrictive, and provides an environment that is more comfortable and conducive to capturing real world behavior. We plan to use fNIRS to assess changes in brain connectivity between the auditory cortex, inferior parietal cortex, and frontal cortex as a function of wearing hearing aids. The overarching research hypothesis is that intervention with hearing aids will improve listening comprehension and memory.
Participants with age-related hearing loss who have never worn hearing aids will be randomized to an immediate treatment group or a waitlisted control group. We will assess auditory processing and cognitive abilities before receiving hearing aids, 3 months after receiving hearing aids and 6 months after receiving hearing aids. Additionally, we will measure changes in brain activation in temporal, parietal and frontal lobe activation and connectivity following treatment. Results will inform the benefits of clinical assessment and intervention of age related hearing loss.
This project aligns with the National Alzheimer’s Project Act to “prevent, halt, or reverse Alzheimer’s disease and related Dementia. This study also aligns with plans to expand research in Utah focused on Alzheimer’s Disease and Related Dementias. Because age related hearing loss is highly prevalent, uncommonly treated, and recognized as one of the major risk factors for dementia, this project is of high public health significance and has a strong potential for guiding future research and practice in this area.